Open-PHA® has a large number of hotkey combinations. They are documented in the following tables.
Tip: When working in Open-PHA®, you can call up the hotkey mapping window to display available hotkey combinations by holding down Ctrl + H
| General | |
| Hot Key | Action | 
| Ctrl + H (hold) | Display Hotkey Map | 
| F1 – F10 | Navigate Primary (Horizontal) Toolbar | 
| Ctrl + F1 – F10 | Navigate Secondary (Vertical) Toolbar | 
| Ctrl + N | Create New Study | 
| Ctrl + O | Open Existing Study | 
| Ctrl + S | Save Study | 
| Ctrl + H | Toggle Hotkey Map (Hold) | 
| Alt + F4 | Exit Open-PHA™ | 
| Ctrl + Number | Navigate Primary Dropdown Menu (Above Worksheet) | 
| With Cell(s) Selected – Dark Blue Highlight | |
| Hot Key | Action | 
| Ctrl + C | Copy Selected Cell(s) | 
| Ctrl + X | Cut Selected Cell(s) | 
| Ctrl + V | Paste Cut/Copied Cell(s) | 
| Delete | Delete Selected Cell(s) | 
| Ctrl + Enter | Create New Row | 
| Escape | Deselect Cell(s) | 
| Arrow Keys | Select Neighboring Cells | 
| Ctrl + Up Arrow | Move Row Up | 
| Ctrl + Down Arrow | Move Row Down | 
| Tab | Select Next Cell | 
| Ctrl + Left Mouse | Select Additional Cells | 
| Shift + Left Mouse | Select Many Additional Cells | 
| With Cell(s) Active – Blue Border | |
| Hot Key | Action | 
| Ctrl + Enter | Create New Row | 
| Ctrl + A | Select All Text in Active Cell | 
| Alt + Arrow Key | Make Neighbor Cell Active | 
